Natural Thymocytotoxic Autoantibody and Reactive Antigen in New Zealand Black and Other Mice

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Natural thymocytotoxic autoantibody and reactive antigen in New Zealand black and other mice.

Naturally occurring thymocytotoxic autoantibody (NTA) was detected by cytotoxic test in the sera of very young New Zealand Black mice (within 1 month after birth); the incidence was 100% at 3 months of age. Some mice from other strains also had NTA, but at an older age and with lower incidence and antibody titer. NTA had optimal activity at 4 degrees C but was also strongly reactive at 37 degre...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1971

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.68.7.1412